Study finds diabetes raises levels of proteins linked to Alzheimer's features

Saturday, October 27, 2012

Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's.

Specifically, the Salk team found increases in two hallmarks of Alzheimer's-accumulations of amyloid beta (Abeta) and tau protein-in the brains of diabetic mice, especially in cells surrounding blood vessels. Abeta, the misfolded peptide that is thought in part to cause Alzheimer's disease, aggregated inside astrocytes, star-shaped brain cells that, upon interaction with Abeta, release inflammatory molecules that can destroy neurons. Previously, this had not been shown in mouse models of type 1 diabetes (T1D).

"Our study supports and extends the links between diabetes, aging and Alzheimer's," says senior author Pamela Maher, a senior staff scientist in Salk's Laboratory of Cellular Neurobiology. "We show that type 1 diabetes increases vascular-associated amyloid beta buildup in the brain and causes accelerated brain aging."

The findings suggest that the neurovascular system may be a good candidate for new therapeutic targets to treat Alzheimer's in the early stages of the disease.

Alzheimer's and diabetes are two diseases that are increasing at an alarming rate within the U.S. population. Alzheimer's affects one in 10 Americans over 65 years of age and nearly 50 percent of those over 85. Similarly, more than 8 percent of Americans (approximately 26 million people) have diabetes, with the vast majority of those individuals being over 60.

Maher says her team is uncertain of the precise mechanism behind the increase in Abeta and tau in the mouse brain, but their data suggest that changes in astrocytes, as well as other pro-inflammatory processes and the bonding of proteins with sugar molecules (called non-enzymatic glycation), may contribute.

"Astrocytes play a key role in maintaining nerve cells in the brain," says lead study author Antonio Currais, a postdoctoral researcher at Salk. "Both chronic peripheral inflammation and increased non-enzymatic glycation are associated with diabetes, and these changes may act on the brain to alter astrocyte function, which eventually leads to Alzheimer's-like changes."

All nerve cells are closely connected to blood vessels, as they need nutrients---- especially glucose (sugar) and oxygen---- provided by the blood in order to function. Astrocytes facilitate the transfer of nutrients between blood vessels and cells. The buildup of Abeta at sites where astrocytes interact with blood vessels suggest that this could impair the transfer of nutrients. The type of Abeta localization seen in Maher's mouse models is also found in human Alzheimer's patients

To examine the contributions of diabetes to Alzheimer's-related pathology in the aged brain, the Salk researchers induced T1D in two sets of mouse models. One set, known as SAMP8 mice, undergo accelerated aging and develop early deterioration in learning and memory, as well as a number of brain alterations similar to those found in Alzheimer's. The other set, SAMR1 mice, which in this study came from the same gene pool as the SAMP8 mice, age normally.

Using these mice, Maher and her colleagues addressed how T1D interacts with age to contribute to Alzheimer's-related pathology. They showed that T1D elicits a wide range of pathological changes in the brains of both strains of mice, which are exacerbated by premature aging.

The Salk study is the first to show that these modifications are similar to those seen in old nondiabetic SAMP8 mice and to identify unique pathological changes, such as increases in markers for inflammation, in aged, T1D SAMP8 mice. Unlike most mouse studies of Alzheimer's, Maher's mice were not engineered to produce high levels of human Abeta or tau,so all of their observations came from naturally occurringAbeta and tau.

###

Salk Institute: http://www.salk.edu

Thanks to Salk Institute for this article.

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Source: http://www.labspaces.net/124872/Study_finds_diabetes_raises_levels_of_proteins_linked_to_Alzheimer_s_features__

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Video: Powell on candidates' foreign policy views (cbsnews)

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Ads Featuring Overweight Children Stop ?Sugarcoating? Childhood ...

From Coral Springs Talk?..

Obesity ads in Georgia are making people a little touchy, especially because they involve in-your-face ads featuring overweight children with messages resembling of ?The Truth? anti smoking campaign.

The campaign, called Strong4Life, by Children?s Healthcare of Atlanta was created in 2011 and urges Georgia residents to ?stop sugarcoating? the childhood obesity crisis. State health officials created the campaign after a survey revealed that 75 percent of parents in Georgia who have an overweight or obese child do not think it?s a problem. Since the state has the second worse childhood obesity rate in the country with nearly 40 percent of all children overweight or obese, officials decided to create the campaign.

Critics have accused Children?s Healthcare of humiliating kids and their parents, the same parents who watched as their children?s weight ballooned.

Linda Matzigkeit, senior vice president at Children?s Healthcare who leads the wellness projects told The Atlanta Journal-Constitution that 85 percent of people who have seen the ads view them positively.

?We have to do something about this or our state is in jeopardy. It?s not good for business if your state has the second highest obesity rate. Obese children turn into obese adults.?

To read the full story?..Click here

This entry was posted in Health / Fitness Articles and tagged Childhood Obesity, Len Saunders by Len Saunders. Bookmark the permalink.

Source: http://www.lensaunders.com/wp/?p=5535

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Gautam Gambhir rues KKR's poor batting performance ? Cricket ...

Gautam Gambhir rues KKR?s poor batting performance ? Cricket News Update

Kolkata Knight Riders? skipper Gautam Gambhir expressed his disappointment with his side?s poor batting performance in their first Champions League Twenty20 match at the SuperSport Park in Centurion on October 13, which saw them losing to the Delhi Daredevils by a margin of 52 runs.

?We played every badly and it was an embarrassing batting performance from us,? he said after the conclusion of the match. ?But it is long way to go. We have the talent and we will come back into the tournament.

?... these things happen,? he continued. ?Sometimes you can't hold on to the momentum. It was a good wicket. One of us had to bat through. If one of our top four got 70, we would have won.?

The KKR, champions of this year?s edition of the Indian Premier League, faced off against the Delhi Daredevils, who came third in the same tournament. The team won the toss and elected to field first, with the bowlers ? among them Sunil Narine (4-0-21-3) and Lakshmipathy Balaji (4-0-61-2) ? putting forth a lukewarm performance, which saw the Daredevils posting a final target of 160 by the end of 20 overs.

While the target appeared more than achievable, however, the KKR crashed spectacularly when they stepped up to the crease for their turn at bat.? The Daredevils? Irfan Pathan (4-0-19-2), Morne Morkel (4-1-25-2), and Umesh Yadav (4-0-13-2) went on a rampage, completely demolishing the Knight Riders? top order.

?Credit to Irfan Pathan and Morne Morkel, and all Delhi fast bowlers. They bowled really well,? Gambhir admitted after the match.

Pathan swept both KKR openers ? wicketkeeper batsman Manvinder Bisla (1) and skipper Gambhir (0) ? off the crease in the very first over, and Morkel followed up with the wicket of veteran batsman Brendon McCullum (0) in the very next over. Jacques Kallis retired hurt on duck, and that took care of the Knight Riders? top order.

Manoj Tiwary top-scored for the team with 33, but the remainder of the batting order failed to make any significant efforts, and the KKR collapsed at 108, with 7 wickets down, by the end of 20 overs.

Source: http://blogs.bettor.com/Gautam-Gambhir-rues-KKRs-poor-batting-performance-Cricket-News-Update-a194636

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German Bundestag president calls for temporary stop to EU expansion

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Associate Teacher ? Rivier University (Nashua, NH)

This is a syndicated post from CatholicJobs.com. [Read the original article...]

ASSOCIATE TEACHER
Education: University/College, FT Employee
Rivier University (Nashua, NH)

ASSOCIATE TEACHER
LANDRY EARLY CHILDHOOD CENTER
(Full-time; 40 hrs/week, 52 wks/yr)

OVERVIEW: To provide formal and informal instruction and care for children enrolled in the University?s Early Childhood Center, under the direction of a certified teacher. In this position you may provide paraprofessional assistance to children with special needs.

DUTIES & RESPONSIBILITIES:
? Assist in teaching and supervising children, implementing appropriate educational curricula, leading/overseeing a wide range of daily activities, and providing general care for the children as appropriate for their age. Serve and supervise meals and/or snacks. Participate in field trips and special events. Maintain a safe indoor and outdoor environment for the children.
? Assist teachers in planning daily lessons and activities, adapt general classroom materials/methods as indicated by the teacher, assist with/carry out a variety of daily classroom management tasks.
? Implement individualized instructional plans and programs for assigned special needs children, under the direction of classroom, special education and/or other certified teachers, working with children individually and/or in small groups.
? Administer assessments to individual or small groups of students.
? Assist in developing, compiling and organizing instructional materials, under the direction of teaching staff.
? Implement behavior management/modification plans for individual children.
? Instruct children in basic life skills, such as acceptable social behavior, dressing/undressing for outdoors, toileting, care of belongings, insertion of hearing aids and use of other assistive devices and special equipment, and the like.
? Assist children as required with toileting, eating, transport in and transfer to/from wheelchairs, walkers and similar devices, and other physical needs. Check and adjust hearing aids. Lift and carry children as required.
? Assist in implementing physical therapy and other specialized programs for children.
? Accompany/supervise/chaperone children, individually or in groups, while traveling to/from various locations, such as field trips.
? Observe and record data on various aspects of student progress and behavior according to established protocols.
? Assist in evaluating children?s progress, problems and needs, developing teaching and behavior management strategies and instructional plans, and so forth. Participate in meetings, parent conferences, informal daily parent communications, and the like as requested/appropriate.
? File student work, instructional materials, reports, and similar written documents. Enter data into and retrieve information from computerized records.
? Operate a variety of office machines to produce instructional materials, including photocopier, laminator, and the like. Produce instructional materials, student work, reports, records, and other written documents using word-processing and other types of software.
? Plan, put up and take down bulletin board and other displays.
? Work with teachers and senior paraprofessionals to improve and expand teaching and counseling skills, understanding of specific disabilities, knowledge of school rules/policies/procedures/practices/philosophies, and so forth.
? Attend staff meetings, in-service and outside training and development activities, participate on committees as requested.
? Complete a minimum of one course per year towards a certificate, Associates or B.A, if candidate does not hold a degree.

QUALIFICATIONS:
? Associates Degree or Bachelor?s Degree in Early Childhood Education or related major
? Minimum of 9 credits in ECE, with at least three credits in Child Growth and Development, and 2 to 4 years of relevant experience and/or post-secondary education, or a combination of education and experience from which comparable knowledge and skills are acquired. Relevant experience working with infant through pre-school age children.
? The ability and willingness to support the mission of the University, in all daily activities.
? Good general understanding of standard child care operations, and familiarity with pre-school classroom management and teaching methods.
? Familiarity with various types of disabilities desirable.
? Good organizational skills, basic typing/keyboarding and other basic computer skills.
? CPR, first aid, and basic health care training required.
? Ability to show patience, respect and compassion in working with children.
? Ability to respond calmly and efficiently to various types of emergency situations.
? Ability to exercise a high level of discretion with regard to sensitive confidential student information.
? Ability to assist children physically as required, including lifting and carrying in specific cases.
? Ability to work cooperatively with classroom and special services teachers, as well as other school personnel and consultants; and to deal courteously and efficiently with parents in coordinating daily activities.

APPLICATION INSTRUCTIONS:
Review of applications will begin immediately and continue until the position is filled. Submit a cover letter stating salary expectations, resume, and the names and numbers of 3 professional references to: Human Resources, RIVIER UNIVERSITY, 420 South Main Street, Nashua, NH 03060, or email to [email?protected] No agencies please. EOE (10)

Source: http://www.dfwcatholic.org/associate-teacher-rivier-university-nashua-nh-55109/.html

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NextGuide iPad app continues its fight against boring grids, adds Amazon, gestures and more

There's more than a few apps (and even DVRs) that promise to help you find something to watch, but one of the more interesting efforts came from Dijit Media's NextGuide app for the iPad. It launched its assault on the old grid-style layout last month, and an update rolling out is adding listings for more content from Amazon VOD and Prime streaming, plus support for new gestures like two finger swipe between show cards, pinch to hide and more. The "Your Picks" algorithms that attempt to figure out what else you may like before you do have been tweaked, and it can also pull up more information about any show or movie with saved searches and Wikipedia bio lookups. Hit iTunes to give the free app a shot, and see if this is a push in the right direction for your TV watching experience.

Filed under: Home Entertainment, Tablets, HD

NextGuide iPad app continues its fight against boring grids, adds Amazon, gestures and more originally appeared on Engadget on Fri, 12 Oct 2012 18:01:00 EDT. Please see our terms for use of feeds.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/sRpg3A0dU78/

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A Life Full Of Leisure At Your Service Near Holborn Hotels London

London is a spectacular city to plan a leisure vacation. Tourists from all round the world visit this city to explore some fun things to do. Holidaymakers in London will find ample leisure activities including luxury spa, swimming, and many more. If you choose a central area such as Holborn, you will get enough time to relax or spend some exciting vacations in the capital. This area is surrounded by many health and beauty centres, parks, and sport activity centres to rejuvenate your body and soul.

If you pick any top luxury, cheap, or secret hotels in Holborn, you will get an easy access to these destinations. Stay at the best London hotel and enjoy a life full of leisure at these sites:

Elemis Spa
Elemis is more than just a spa, offering wide range of therapies from Japan, Morocco, Bali, Tibet, and Thailand. You will get everything here from a luxurious day spa to a variety of holistic treatments. Hidden down the Bond Street, this spa provides a calm oasis of beautification in the middle of the London city.

Brown Hart Gardens
This fabulous garden is just off the Oxford Street closely located to Holborn hotels London. The terrace garden at the Brown Hart Gardens is a pleasant oasis between the Gilbert and the Binney Street. Ancient domes and stone pillars remind you of the classic Italian Garden, which was replaced by an electricity station.

Urban Golf
Urban Golf in Soho is a perfect venue for golfers who can play in any of the 52 golf courses of the world. It features state of the art golf stimulators and a chic cocktail bar and lounge to give you a vacation time in London. In its sleek and stylish surroundings, you can chill out or play championship golf matches with your friends.

Dolphin Swimming Club
Located in Malet Street, Bloomsbury, this Dolphin Swimming Club is perfect for swimmers of all levels. From swimming lessons for children and special sessions for aqua phobic adults, you can try them all here.

Phoenix Garden
Hidden from most tourists, Phoenix Garden is a tranquil haven for London wildlife. You will see birds of all shapes and sizes here along with some frogs and tadpoles in the pond. This beautiful community garden in the West End is maintained using wildlife gardening and sustainable techniques.

So, head down to these sights near Holborn hotels and enjoy a relaxing leisure vacation in London.

About the Author:
John Rodricks is an associate editor of a website which offers secret hotels in Holborn. The travelers can pick from a varied range of hotels near Holborn tube station.

Source: http://www.articlesnatch.com/Article/A-Life-Full-Of-Leisure-At-Your-Service-Near-Holborn-Hotels-London/4210014

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VP debate tees up closing issues for Romney, Obama

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Active Travel

About Active Travel, part of the Alliance Group

Building on its solid reputation for having a fast and efficient service at the best possible prices, Active Travel has expanded its leisure travel network to offer a complete range of holiday packages worldwide.

Speicialising in Honeymoon Travel

Exotic, exclusive and full service honeymoon packages are available from Active Travel as well as tailor made packages made to match the couple?s specific requirements.

Offering packages in a multitude of countries, below one can find a list of the countries that Active Travel provides packages to:

• Antigua ? Argentina ? Bahamas ? Bali ? Canada ? China ? Costa Rica ? Cuba ? Cyprus ? Dubai ? Ecuador ? Egypt ? Greece ? India ? Indonesia ? Italy ? Jamaica ? Japan ? Madagascar ? Malaysia ? Maldives ? Mauritius ? Mexico ? Nepal ? Panama ? Peru ? Philippines ? Portugal ? Seychelles ? Singapore ? Spain ? Sri Lanka ? St. Lucia ? Thailand ? United States of America & Vietnam.

Active travel also specialises in honeymoon packages such as cruises, safaris and the?exclusive Sandals ultra luxury, all inclusive resorts in the Caribbean.?

Skiing Holidays ? by Active Travel

? Individual & group departures to the best ski resorts in Europe! We are the exclusive local agents for Chalet Chez Nous, Chalet La Petitta and the Etoiles des Neiges in Sauze D?Oulx ? forming part of the ?Milky Way? in Italy and having over 400km of pistes. Our packages cater for all level of skiers at truly affordable prices.

Family breaks

Kids just want to have fun! Whatever you are looking for, be it family resorts, fun parks, beach holidays, mountain resorts, skiing, ?Agriturismo? we have just the break for you!

Football & other sports

If you are looking for football, we have packages available for the English, Italian, Spanish & German Football Leagues as well as World Cup, Champions League and other cup finals. Other major sporting events are available including Formula 1, International Tennis Tournaments including Grand Slams.

Concert, Opera & Ballet lovers

Be there to watch your favourite artists on stage. We offer affordable packages to most of the top shows in Europe.

Hotels Worldwide

Don?t book online before comparing the price with us! In most cases we are cheaper and more reliable than the internet booking engines. We also offer the best prices at the most popular hotels in central London.

Contact HRG Active Travel Ta? Xbiex

C:Tim Staff
E:tim@alliancemalta.com
A:HRG Active Travel, 4, Abate Rigord Street, Ta? Xbiex, XBX 1127, Malta.
W: Visit Active Travel Website

Find Active Travel in Ta?Xbiex on the map

Source: http://allmaltaonline.com/weddings/active-travel/

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TSX falls at open on weak U.S. earnings outlook

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Soccer-Scheduling issues irk Asian sides fighting on two fronts

SINGAPORE, Oct 11 (Reuters) - Jordan coach Adnan Hamad has

bemoaned scheduling conflicts as his attempts to steer the side

through to a first World Cup finals were complicated by having

to also negotiate an Asian Cup qualifying campaign.

The Asian Football Confederation (AFC) conducted the draw

for the 2015 Asian Cup qualifiers in Australia on Tuesday and

Jordan were one of seven teams involved that are also still in

contention for a place at the World Cup in Brazil in 2014.

Japan and South Korea avoided Asian Cup qualifying courtesy

of being in the top-three finishers at the last Asian Cup, along

with runners-up Australia, who will host the 2015 tournament.

But Jordan, Qatar, Oman, Iran, Lebanon, Uzbekistan and Iraq

will all be required to handle overlapping campaigns.

The Asian Cup matches will begin in February and run through

to March 2014 with the top two sides from each group advancing

to the finals. The World Cup qualifiers are ongoing with the

final match date scheduled for June 18 next year.

Jordan currently hold one of the top-two automatic

qualifying berths for Brazil after their shock 2-1 home win over

Australia in Group B last month and travel to face bottom-placed

Oman next week.

In the regional qualifiers, Jordan were drawn with Syria,

Singapore and Oman but Hamad was only concentrating on the

fourth round World Cup clash in Muscat.

"We have a very good to chance to reach the (Asian Cup)

finals, but there is a problem as some of the matches are going

to be played at the same period with the World Cup qualifiers,"

Hamad told the Asian Football Confederation.

"We must focus now on the upcoming two matches in the World

Cup qualifiers, then we will start thinking about the Asian Cup

qualifications. We must give it (the World Cup qualifications)

full attention as we want to reach the finals."

Qatar were drawn alongside Bahrain, Yemen and Malaysia in

Group D of Asian qualifying but their Brazilian coach Paulo

Autuori shared Hamad's view of only thinking about next

Tuesday's World Cup clash.

Qatar are currently third in their five-team World Cup group

behind South Korea (seven points) but level on four points with

Iran and Lebanon with the Uzbeks two points back in last.

"We only think about the match with Uzbekistan in World Cup

qualifying now," Autuori told the AFC. "We will start thinking

about the Asian Cup qualifiers after the Uzbekistan match."

Lebanon have enjoyed some rapid progress under German coach

Theo Buckner and are competing in the fourth round of World Cup

qualifiers for the first time.

Expected to be the whipping boys of Group A, Lebanon stunned

Iran 1-0 last month and Buckner talked up his side's chances of

reaching the Asian Cup finals after being drawn alongside

Thailand, Kuwait and Iran, again.

"We must work very hard to keep the same level we reached

with the national team," Buckner told the AFC.

"Our chances are there to reach the Asian Cup, but we must

prepare the team in a good way to make them capable of playing

the World Cup qualifications and Asian Cup qualifying matches at

the same time."

- - - -

2015 Asian Cup qualifying draw

Group A

Jordan

Syria

Oman

Singapore

Group B

Iran

Kuwait

Thailand

Lebanon

Group C

Iraq

China

Saudi Arabia

Indonesia

Group D

Qatar

Bahrain

Yemen

Malaysia

Group E

Uzbekistan

United Arab Emirates

Vietnam

Hong Kong

(Reporting by Patrick Johnston; Editing by John O'Brien)

Source: http://news.yahoo.com/soccer-scheduling-issues-irk-asian-sides-fighting-two-083218752--sow.html

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Previewing the Vice Presidential debate, Part One (Powerlineblog)

Share With Friends: | | Politics - Top Stories News, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/254504248?client_source=feed&format=rss

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Video: Nick Offerman reveals ?Parks and Rec? love interest

>> happening in your neck of the woods.

>> and that's your latest weather.

>> all right, al. thanks. we want to bring back nick offerman and his famous mustache. "parks and rec" now in the fifth season. good morning to both.

>> thank you. good morning.

>> we love that show around here. i have to say, are you now at the point you get renewed for the season, there's no trepidation, will we or won't we?

>> i don't know, i think network tv is in a precarious position and we can no longer tell if the numbers from the nielsen ratings are indicative of what's going on because so many of the young smart people are watching it online. and so there's always -- there's always, we never feel really comfortable. we're always really relieved like, whew.

>> now you're in the fifth season, you get a little love interest here with lucy lawlis? wow.

>> tell us about that.

>> what's up with that?

>> it's -- i've never in 20 years of a professional acting such a champion of a lady in front of me. i've played her plumber and her bus driver, but i've never played the guy with her.

>> can a romantic comedy be far behind at this point?

>> gosh, i don't know. that seems like a stretch to me, you never know.

>> i understand your ex-wife tammy 2 back on the scene played by your own wife megan malali, how is that going to work.

>> it's going to be very interesting that tammy 2 is quite a monster and she's gotten wind of ron's new love interest . some havoc will be wreaked.

>> and you and your wife are doing all kinds of projects together.

>> we are. we have so much fun. we get to work on films together. we have one opening on the 12th called "smashed," which is really good. and she has a new band called nancy and beth. and they've been opening for a live show i do. and we have so much fun getting to play together.

>> cool.

>> it's a blessing.

>> play together, stay together.

>> yes, ma'am.

>> i love it.

>> the mustache, megan, and yourself.

>> the mustache gets a little more attention than i do. it's early.

>> we're so happy to see you. thanks for hanging out with us today.

>> thanks for having me.

>> and you can catch "parks and rec" tonight 9:30/8:30 central

Source: http://video.today.msnbc.msn.com/today/49373402/

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Rev Clinton Chisholm accused of pushing ?bad science? in regards ...

as posted on Anti Gay Fact Check?a new gay blogger on the scene and I am happy that the tool was rejected by some in LGBT advocacy has now become the very way to speak out on issues, the young blogger has been doing his homework thus leaving me time to see other points of view and focus on other areas.

AGFC wrote:

Rev. Dr. Clinton Chisholm who is a lecturer at the Jamaica Theological Seminary quotes some studies to denounce the ?ex-gay? therapy ban in California for minors in an effort to sound smart.

As usual, we at AGFC are ahead of the game and we know when the anti-gay movement/?ex-gay? mythologists not only tell lies but have no clue what they themselves are even talking about.

?Nothing in the world is more dangerous than sincere ignorance and conscientious stupidity? ? Martin Luther King, Jr.

?

We debunked his article entitled ?That Puzzling California Law? below which you can read here:?http://jamaica-gleaner.com/gleaner/20121009/cleisure/cleisure3.html

1)

The ostensibly progressive and rights-protecting California law banning all reparative (?conversion?) therapy for minors is very puzzling and raises some very awkward questions.

What is it about homosexual orientation or behaviour (if unwanted) that makes it so uniquely resistant to psychotherapeutic behaviour-modification interventions? I say uniquely resistant because such clinical interventions are utilised for a whole range of unwanted behaviours, including alcoholism, sexual/gender identity issues, anxiety disorders (phobias), unlawful sexual urges, etc.

What then is the real motivator behind the rights veneer of the California law?

We should also factor in religious interventions. Bottom line: Is there any unwanted behaviour for which clinical behaviour-modification or spiritual intervention is ruled out, a?priori, and why?

Now first of all Mr. Chisholm needs to understand three things. He needs to?understand?that homosexuality is not a behaviour but a sexual?attraction?to?the?same sex. He also needs to understand that reparative/conversion therapy is not modifying same-sex behaviour but same-sex?attractions. He also needs to understand that homosexuality is not listed as a mental disorder by any mental health organisation. Can homosexuality be compared to alcoholism, phobias and anxiety disorders which are all classified as?psycho-pathologies? What is so unique about homosexual orientation that Rev. Chisholm would want to force a child to ?change it?? Do you change a child?s sexual orientation to please religiously motivated political groups or do you help them to overcome the social pressures which cause them to not be pleased with their sexual orientation?

Why does Mr. Chisholm?believe?that the Californian law is giving anyone rights? In fact, the law is there to protect the well being of children. Now, the American Psychological Association(APA) in 2009?produced?a 130 page report on the efficacy of sexual orientation change efforts(SOCE) after reviewing 83 studies done from from 1960-2007. In it they said:

?We found that there was some evidence to indicate that individuals experienced harm from SOCE. Early studies documented iatrogenic effects of aversive forms of SOCE. These negative side effects included loss of sexual feeling, depression, suicidality, and anxiety. High drop rates characterized early aversive treatment studies and may be an indicator that research participants experienced these treatments as harmful?.

See here:?http://www.apa.org/pi/lgbt/resources/therapeutic-response.pdf

Another study done by?Schroeder & Shidlo in 2001 on 202 so called ?ex-gays? found that many of them experienced harm from the ?therapy?. The study?s summary said:

?We found evidence that many consumers of failed sexual orientation?therapies experienced them as harmful. Areas of perceived?psychological harm included depression, suicidality, and?self-esteem. In the case of aversive conditioning and covert sensitization,?harm included intrusive flashback-like negative imagery?that was associated with serious long-term sexual dysfunction.?Areas of perceived social harm included impairment in intimate?and nonintimate relationships. Some religious participants also?reported experiencing spiritual harm as a result of religious?therapy.?

See study here:?Schroeder & Shidlo?s study

Is this not reason to protect children from so-called therapies which are harmful? Read our post about an experience of a child who went through this ?therapy?(http://antigayfactcheck.org/2012/07/15/forced-ex-gay-therapy-led-child-to-his-death/). The results were disastrous.

Is ?ex-gay? the same as heterosexual?

2)

What then should one make of the implications of two articles in the American Journal of Psychiatry, namely, ?The Masters and Johnson Treatment Program for Dissatisfied Homosexual Men?, American Journal of Psychiatry, 141 (1984), 173-81 and E. Mansell Pattison and Myrna Loy Pattison, ?Ex-Gays: Religiously Mediated Change in Homosexuals?, American Journal of Psychiatry, 137 (1980), 12?

The Masters & Johnson treatment programme reports conversion success rate at 65 per cent after a five-year follow-up.

As usual the religious right loves to quote studies that other politically motivated ?family? groups give to them but never bother reading or researching on these studies themselves.

The study done by Masters and Johnson entitled ?The Masters and Johnson Treatment Program for Dissatisfied Homosexual Men? proves this well as Mr. Chisholm doesn?t even realise that one of the authors, Virginia Johnson, admitted in 2009 that the results were fabricated. Fabricated results masquerading as truth? Is this some deception campaign of the anti-gay movement? The famous science magazine, Scientific American, did a report on this. It said:

?Prior to the book?s publication, doubts arose about the validity of their case studies.?Most staffers never met any of the conversion cases during the study period of 1968 through 1977, according to research I?ve done for my new book Masters of Sex . Clinic staffer Lynn Strenkofsky, who organized patient schedules during this period, says she never dealt with any conversion cases.?Marshall and Peggy Shearer, perhaps the clinic?s most experienced therapy team in the early 1970s, says they never treated homosexuals and heard virtually nothing about conversion therapy.

Eventually Kolodny approached Virginia Johnson privately to express his alarm. She, too, held similar suspicions about Masters? conversion theory, though publicly she supported him.?The prospect of public embarrassment, of being exposed as a fraud, greatly upset Johnson, a self-educated therapist who didn?t have a college degree and depended largely on her husband?s medical expertise.

With Johnson?s approval, Kolodny spoke to their publisher about a delay, but it came too late in the process.??That was a bad book,? Johnson recalled decades later. Johnson said she favored a rewriting and revision of the whole book ?to fit within the existing [medical] literature,? and feared that Bill simply didn?t know what he was talking about. At worst, she said, ?Bill was being creative in those days? in the compiling of the ?gay conversion? case studies.?

http://www.scientificamerican.com/article.cfm?id=homosexuality-cure-masters-johnson

This is the third time we have heard about this Masters and Johnson study. The more they quote it is the easier our job gets.

As for the study ?Ex-Gays: Religiously Mediated Change in Homosexuals?, well we have a?real?interesting story to tell about this one. In 1978, two outside psychiatrists, were allowed to interview members of Exodus International, the worlds largest ?ex-gay? organisation which recently distanced itself from reparative therapy. Of the ministry?s 300 members at the time, 30 were selected by the ministry staff as having changed from exclusively homosexual to exclusively heterosexual in orientation. The researchers interviewed the 30 and determined that only 11 had really been largely ?cured? of their homosexual orientation because they had remained celibate. However, 8 of the 11 continued to have a homosexual or bisexual orientation because they still reported homosexual dreams, fantasies and/or impulses. Therefore only 3 out of 300 members who underwent this ?therapy? reported changing to heterosexual. This would mean that the therapy has a 1% success rate if we were to?believe?the 3 men. No follow-up study was done and the subjects were taken from a political organisation which probably skewed the results. The study has obvious methodological flaws.

The Pattison study included a table describing their interview findings with the 11 subjects (from page 1555, see below). Bussee was subject number two and Cooper was number one.

However something happened in 1979 to two of the participants. Michael Bussee and Gary Cooper left the organisation, divorced their wives and ended up marrying each other. These two leaving as failures prove that the study was very flawed. In fact, Michael Bussee today criticised the study and even the organisation he helped to found, Exodus International.

http://www.religiondispatches.org/archive/sexandgender/5374/participant_discredits_the_original_ex-gay_study/

Do we want to put children through a therapy known to cause harm which according to a flawed study only resulted in 1% success?

3)

In the cutting-edge book?Ex-Gays? A Longitudinal Study of Religiously Mediated Change in Sexual Orientation?by Stanton L. Jones & Mark A. Yarhouse, Downers Grove, IL: IVP Academic, 2007, the authors found, contrary to the belief of certain clinicians, that change is possible.

Though operating with an upfront Christian commitment, Jones and Yarhouse conceded that they did not find that change is possible for everyone. They write: ?The fact that some human beings can break the four-minute-mile barrier establishes that running a four-minute mile is not impossible, but that same fact does not establish that anyone (every human being) can break the four-minute-mile barrier.?

So, then, are the California legislators unaware of the pro-change pieces of literature mentioned above and published in their own country? Behold, I show you a mystery, or perhaps mischief!

The study by Jones and Yarhouse was rejected by the American Psychological Association for methodological flaws. The authors themselves even ?said on their website?(http://www.exgaystudy.org/ex-gays/responses-to-criticism)?in regards to what ?conversion? means that: ?Most of the individuals who reported that they were heterosexual at Time 3?did not report themselves to be without experience of homosexual arousal, and did not report heterosexual orientation to be unequivocal and uncomplicated.? In other words, the people who claimed they ?changed? still experienced homosexual attractions and were thus bisexual. The study did not indicate as to whether or not they were bisexual before the study however. This study was clearly not a study to prove that homosexuals can ?change? into heterosexuals but that some subjects experienced attractions to the opposite sex after ?therapy?. Without knowing whether or not they were also attracted to the opposite sex before the study is a methodological flaw. The authors single sentence summary says: ?In short,?the results do not prove that categorical change in sexual orientation is possible for everyone or anyone, but rather that meaningful shifts along a continuum that constitute real changes appear possible for some.?

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Posted on October 10, 2012 at 10:19 AM in Bloggers Writings, Ethics, Ex-gay, Human Rights Issues, Hypocrisy and homophobia, Psychological References, Publications, Religion, Reparative Therapy, Stereotypes, Stigma and Discrimination, Theocracy ??|??RSS feed |?? Respond ??|?? Trackback URL

Source: http://glbtqja.wordpress.com/2012/10/10/rev-clinton-chisholm-accused-of-pushing-bad-science-in-regards-to-ex-gay-therapy/

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IOF Young Investigator Awards recognize research excellence at IOF--PAOS Jordan Meeting

Public release date: 1-Oct-2012
[ | E-mail | Share ]

Contact: L. Misteli
info@iofbonehealth.org
41-229-940-100
International Osteoporosis Foundation

Five researchers were presented with 'IOF Young Investigator Awards' at the International Osteoporosis Foundation (IOF) Regionals - 2nd Middle East & Africa Osteoporosis Meeting and the 6th Pan Arab Osteoporosis Congress PAOC'6 on September 30, 2012. The Meeting was held at the King Hussein Bin Talal Convention Centre, Dead Sea, Jordan.

IOF is dedicated to advancing scientific knowledge on osteoporosis, and in particular to encouraging young researchers in all parts of the world to engage in bone research. As a sign of this commitment, IOF offers annual Young Investigator Awards at its regional meetings.

The prestigious grants were awarded to the presenting authors (40 years old or younger at the time of the Meeting) of the top five ranking abstracts. Each winner received USD 1,000 and was invited to present his or her work during a special plenary session.

The abstract titles and winning authors at the IOF-PAOS Meeting were:

• Sex difference in the relation between fat mass index and hip bone mineral density in a group of Lebanese adolescents and young adults. Rawad El Hage (Lebanon)
• Effects of low dose X-irradiation on formation, proliferation and activity of osteoblasts and osteoclasts in vitro. Yekun. Deng (China)
• Vitamin D synthesis in Caucasian and South Asian women following ultraviolet radiation. Ohood A. Hakim.(United Kingdom)
• The controversy over initiation, continuing or stopping treatment when osteoporotic fracture occurs. Rami Eid (Syria)
• Utility of Q Fracture Score in Iraqi women suspected to have vertebral fracture. Ahmad Abdulbari (Iraq)

The prize winners and an additional group of investigators aged 40 years or under were also invited to attend the first "IOF Young IOF Young Investigator Mentoring Programme". The exclusive hands-on course was led by renowned faculty and focused on research, writing publications and delivering presentations.

###

About IOF

The International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization devoted to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members including committees of scientific researchers, patient, medical and research societies, and industry representatives from around the globe share a common vision of musculoskeletal health without fragility fractures. IOF now represents more than 200 societies in all region

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 1-Oct-2012
[ | E-mail | Share ]

Contact: L. Misteli
info@iofbonehealth.org
41-229-940-100
International Osteoporosis Foundation

Five researchers were presented with 'IOF Young Investigator Awards' at the International Osteoporosis Foundation (IOF) Regionals - 2nd Middle East & Africa Osteoporosis Meeting and the 6th Pan Arab Osteoporosis Congress PAOC'6 on September 30, 2012. The Meeting was held at the King Hussein Bin Talal Convention Centre, Dead Sea, Jordan.

IOF is dedicated to advancing scientific knowledge on osteoporosis, and in particular to encouraging young researchers in all parts of the world to engage in bone research. As a sign of this commitment, IOF offers annual Young Investigator Awards at its regional meetings.

The prestigious grants were awarded to the presenting authors (40 years old or younger at the time of the Meeting) of the top five ranking abstracts. Each winner received USD 1,000 and was invited to present his or her work during a special plenary session.

The abstract titles and winning authors at the IOF-PAOS Meeting were:

• Sex difference in the relation between fat mass index and hip bone mineral density in a group of Lebanese adolescents and young adults. Rawad El Hage (Lebanon)
• Effects of low dose X-irradiation on formation, proliferation and activity of osteoblasts and osteoclasts in vitro. Yekun. Deng (China)
• Vitamin D synthesis in Caucasian and South Asian women following ultraviolet radiation. Ohood A. Hakim.(United Kingdom)
• The controversy over initiation, continuing or stopping treatment when osteoporotic fracture occurs. Rami Eid (Syria)
• Utility of Q Fracture Score in Iraqi women suspected to have vertebral fracture. Ahmad Abdulbari (Iraq)

The prize winners and an additional group of investigators aged 40 years or under were also invited to attend the first "IOF Young IOF Young Investigator Mentoring Programme". The exclusive hands-on course was led by renowned faculty and focused on research, writing publications and delivering presentations.

###

About IOF

The International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization devoted to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members including committees of scientific researchers, patient, medical and research societies, and industry representatives from around the globe share a common vision of musculoskeletal health without fragility fractures. IOF now represents more than 200 societies in all region

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-10/iof-iyi100112.php

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